GSK Reports Results from the P-III (EAGLE-1) Study of Gepotidacin for the Treatment of Urogenital Gonorrhoea (GC)
Shots:
- The P-III (EAGLE-1) study compares the safety & efficacy of gepotidacin vs ceftriaxone + azithromycin for treating adults & adolescents (n=600) with uncomplicated urogenital gonorrhoea
- The study’s 1EP, the microbiological response at the ToC visit 3-7 days after treatment, depicted gepotidacin's (oral, two doses of 3,000mg) non-inferiority to ceftriaxone (500mg, IM) + azithromycin (1,000mg, oral) for urogenital gonorrhea
- Gepotidacin is a bactericidal antibiotic that hinders bacterial DNA replication & inhibits two different Type II topoisomerase enzymes for most pathogens. It is also being evaluated for treating uncomplicated urinary tract infections (uUTI)
Ref: GSK | Image: GSK
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